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Downloadable slides on the evolving ADC landscape in the management of patients with HER2-negative metastatic breast cancer, current role of TROP2-directed ADCs, efficacy and safety of TROP2-directed ADCs in advanced breast cancer, ways to optimize adverse event recognition, early intervention and quality-of-life preservation for patients receiving TROP2-directed ADCs, key ongoing trials of TROP2-directed ADCs in breast cancer, role of nurses in providing optimal care for patients receiving ADCs, and multidisciplinary team coordination and shared decision-making to improve patient care.